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AsteraAstera

Research Associate, Rodent Surgery & Behavior

Performs mouse survival surgeries, behavioral training, colony operations, and behavior-rig maintenance for an all-optical neuroscience program. Requires hands-on cranial-window and headbar implantation, stereotaxic viral injections, and experience producing healthy, long-lived preparations.

About the job

Responsibilities

  • Perform mouse survival surgeries under aseptic technique and IACUC-approved protocols, including stereotaxic AAV viral-vector delivery, chronic cranial-window implantation, and headbar installation.
  • Run head-fixed behavior training on sequence working-memory tasks, including daily training, data collection, and rig upkeep.
  • Build and maintain behavior rigs, including Bonsai and Harp control systems and lickport hardware.
  • Manage the mouse colony and coordinate animal sourcing, health, and readiness with vivarium and veterinary staff.
  • Maintain careful shared records of surgeries, training histories, and preparation quality for scientific continuity and compliance.
  • Work with scientists conducting all-optical experiments to coordinate preparation, imaging, and perturbation.

Requirements

  • Current hands-on experience performing mouse survival surgery, including chronic cranial-window implantation, headbar installation, and stereotaxic viral injections.
  • Demonstrated record of consistently healthy, long-lived surgical preparations.
  • Meticulous technique and ability to sustain high-quality work at volume.
  • Willingness to work with standardized shared infrastructure, surgical preparations, rigs, and records.
  • Strong commitment to animal welfare and open science.

Nice to Have

  • Experience with head-fixed behavior training, especially working-memory or sequence tasks.
  • Python scripting experience and familiarity with Bonsai, Harp, or comparable behavior-control tools.
  • Experience building and maintaining behavior rigs, including lickport and custom hardware.
  • Experience with two-photon imaging or optogenetic stimulation in awake mice.
  • Colony management experience and coordination with vivarium staff.

Education

  • BS or BA in neuroscience, biology, bioengineering, or a related field, or equivalent hands-on experience. Demonstrated skill and relevant experience are valued above credentials.

Compensation and Benefits

  • Salary range: $80,000-$120,000.
  • Comprehensive benefits package, commensurate with experience.

Skills

Mouse Survival Surgery, Cranial-Window Implantation, Headbar Installation, Stereotaxic Injections, Aav Viral Vectors, Head-Fixed Behavior, Python, Bonsai, Harp, Lickport Hardware, Two-Photon Imaging, Optogenetics, Iacuc, Colony Management

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