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PhyloPhyloSouth San Francisco, CA

Member of Technical Staff - System Engineering

Builds and operates core distributed systems, infrastructure, and service architecture for Phylo's agentic AI platform, ensuring reliable scaled execution across cloud and enterprise environments. Requires 3+ years in backend/infrastructure engineering with Kubernetes and cloud expertise.

200k – 300k/yr
On-siteDevOps / SRE

About the role

Responsibilities

  • Design and build production systems that orchestrate agent execution and power AI-driven scientific workloads.
  • Build and operate scalable, reliable infrastructure across cloud, hybrid, and on-prem enterprise environments.
  • Develop systems for sandboxed execution, secure task isolation, and controlled compute environments.
  • Design and implement security, access control, and compliance foundations suitable for enterprise deployments.
  • Partner closely with ML and science teams to translate computational workflows into robust, production-grade distributed systems.

Requirements

  • 3+ years of industry experience in backend, infrastructure, or distributed systems engineering.
  • Strong proficiency in at least one programming language (Python, Go, Rust, or similar).
  • Experience designing and operating distributed systems in production.
  • Deep hands-on experience with containerization and Kubernetes.
  • Experience with infrastructure-as-code tooling (Terraform, Pulumi, or equivalent).
  • Experience operating systems on at least one major cloud provider (AWS, GCP, or Azure).
  • Comfort owning systems end-to-end in fast-moving, high-autonomy environments.

Nice to Haves

  • Experience building enterprise SaaS platform that supports single-tenant, customer hosted deployment patterns.
  • Experience in building R&D infrastructure at Pharma/Biotech.
  • Experience with job orchestration, task scheduling, or workflow engines.
  • Experience with sandboxed or isolated execution frameworks (gVisor, Kata Containers, Firecracker).
  • Familiarity with distributed storage, observability systems, or high-performance compute environments.

Compensation & Benefits

  • Competitive salary and equity share.
  • Full medical, dental, and vision coverage, including free therapy sessions and eyewear stipend.
  • 401(k).
  • Unlimited PTO (US only).
  • Lunch and snacks when in office.
  • Regular team offsites and company events.

Skills

KubernetesTerraformPythonGoRustAWSGCPAzurePulumiDistributed Systems

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