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Scientist

115k – 125kBethesda, MDOnsite7+ YOE
Summary

PhD-level Scientist supporting NIH Clinical Center research on image-guided interventions. Conducts preclinical experiments, develops animal models, analyzes data, and publishes findings. Requires molecular biology expertise and animal surgery skills.

About the role

Responsibilities

  • Develop animal model systems to support the overall mission of the CIO.
  • Select, devise, plan and execute preclinical experiments in the context of the laboratory overall research program.
  • Perform a variety of experimental procedures and preclinical studies of image-guided interventions investigations.
  • Support the planning and execution of research experiments in the context of the laboratory's overall research program.
  • Evaluate new techniques, instruments, and software for potential incorporation into current SOP.
  • Support laboratory staff on research projects and techniques.
  • Work with staff on assay design and method development using an array or experimentation.
  • Maintains laboratory equipment and the training of others in their use.
  • Calibrate, maintain and troubleshoot instruments and equipment in the laboratory.
  • Assist in maintaining adequate space and facilities for ongoing and projected research studies.
  • Provide basic and advanced training in animal care and use procedures to staff.
  • Evaluate, analyze and interpret research data, communicate results and methods in reports, presentations, and manuscripts.
  • Maintain a detailed and up-to-date electronic laboratory notebook detailing all experiments.
  • Coordinate with junior staff to modify research protocols.
  • Work with Principal Investigators in scheduling and prioritizing instrument usage.
  • Present research at national scientific meetings and symposia.
  • Write papers and abstracts detailing research efforts and results for publication in peer-reviewed journals; prepare PowerPoint presentations as appropriate.
  • Provide interpretation of results, guidance, and scientific support to the management team.
  • Search existing literature for new and/or relevant techniques.
  • Mentor junior level scientists.
  • Train staff in a wide variety of techniques used in the laboratory.
  • Investigate the safety and effectiveness of image guided interventions such as embolic therapies, thermal tumor ablation, cardiovascular devices and therapeutics, local or targeted drug delivery, combination products and targeting devices for the treatment of oncologic and vascular disease.
  • Support ideal functioning of the bench and imaging lab.
  • Interact with a multidisciplinary team of scientists, veterinarians and technicians in developing/ordering needed tools for projects.
  • Evaluate new types of experimental approaches and recommend changes to protocols based on knowledge of scientific literature, available facilities and research needs.
  • Determine experimental approaches to be applied in order to evaluate the hypotheses under investigation and for planning and carrying out those experiments.
  • Perform analysis and interpretation of the data to develop strategies for pursuing significant observation and for ensuring accuracy and reproducibility of results.
  • Interpret experimental techniques and procedures.
  • Search all pertinent literature and references.
  • Devise, modify and perform analyses.
  • Evaluate and interpret data and make modifications as needed.
  • Communicate results and methods in reports, presentations and manuscripts for peer reviewed publications and at local, national and international meetings.
  • Coordinate the training of laboratory personnel, research associates, post-doctoral fellows, visiting scientists, students and others in specialized technologies.

Requirements

  • Ph.D. degree in a scientific field.
  • Field of Study: Molecular Biology.
  • Scientific knowledge of molecular biology, biochemistry; ability to learn new techniques, and cell culture.
  • Molecular biological theories and techniques to the work as well as analyzing and evaluating research findings.
  • High level judgment and selectivity in applying theories, techniques and principles to research.
  • Handling of small animals and skill in animal surgery and tissue dissection.
  • Software: PowerPoint, MS Project, MS Access, Outlook, Excel, Word.

Nice-to-Haves

  • Experience with image-guided interventions, embolic therapies, thermal tumor ablation, cardiovascular devices, local or targeted drug delivery, combination products, and targeting devices for oncologic and vascular disease.
Skills
Molecular BiologyBiochemistryCell CultureAnimal SurgeryTissue DissectionPreclinical ExperimentationImage-Guided InterventionsData AnalysisScientific WritingLaboratory Management
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