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General Manager

311k – 389kNew York, NYBoston, MAHybrid8+ YOE
Summary

Lead drug asset development as accountable General Manager, owning strategy, P&L, execution, and cross-functional coordination to drive value inflection with speed and AI leverage.

About the role

Responsibilities

  • Refine and deliver the strategy for the asset and define key results that ladder up to asset objectives.
  • Drive and own business outcomes—including asset P&L, budgets, ROI, and value inflection with speed.
  • Lead a team of full-time and contract team members, forecasting and pulling resources (functional experts, tech, and other services) as needed.
  • Partner with the assigned Tech Lead, Clinical Development Lead, and other functional subject matter experts (e.g., CMC, Regulatory, Data Science) to drive asset strategy and execution.
  • Establish and run team rituals (charters, prioritization touchpoints, etc.) that ensure clarity, accountability, and disciplined execution.
  • Anticipate and surface tradeoffs, risks, and governance needs, while maintaining autonomy for operational decisions.
  • Develop and maintain comprehensive governance tools such as asset development roadmaps, registers and dashboards.
  • Track and manage against success metrics, including milestone adherence, team efficiency and overall asset value.
  • Provide ongoing strategic updates to the Formation Bio Leadership Team, ensuring alignment with broader portfolio and company-level strategy.

About You

  • Outcome-Driven: You optimize for value creation and speed, not process for its own sake.
  • Radically Accountable: You own timelines, budgets, risks, and tradeoffs without relying on matrix ambiguity.
  • AI-Native: You naturally embed AI and automation into team culture, workflows, and decisions.
  • Generalist With Range: You flex across disciplines, knowing when to go deep or bring in expertise and when to rely on the team.
  • Influential Without Authority: You earn trust and alignment among SMEs and functional leaders without direct reporting lines.
  • Structured & Decisive: You run the team like a business—with sharp prioritization, clear charters, and disciplined execution.
  • Comfortable in Ambiguity: You thrive in dynamic environments, simplify complexity, and adapt quickly.
  • Strategically grounded with tactical depth: You seamlessly connect high-level vision to detailed, practical action.
Skills
Asset StrategyP&L ManagementBudget ManagementCross-functional LeadershipRoadmappingGovernanceStakeholder ManagementAI IntegrationRisk ManagementPortfolio Strategy
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