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Senior AI and Large Language Model (LLM) Engineer

Bethesda, MDML EngineeringOnsite3+ YOE
Summary

Leads design, customization, and integration of LLMs into biomedical research workflows and NCBI platforms like PubMed. Requires 3+ years hands-on LLM experience with Python, PyTorch, Hugging Face, and RAG systems; biomedical domain preferred.

About the role

Key Responsibilities

  • Serve as the AI/LLM subject matter expert across product and engineering teams.
  • Collaborate with product managers and technical leads to define AI-enabled capabilities and define the use of LLMs across NCBI platforms (e.g., PubMed and related systems).
  • Develop and implement retrieval-augmented generation (RAG) systems integrating LLMs with large-scale biomedical datasets.
  • Provide architectural guidance on model selection, domain adaptation, evaluation strategies, and deployment approaches.
  • Improve model grounding, factual accuracy, and scientific reliability in domain-sensitive applications.
  • Support engineering teams in productionizing AI solutions, ensuring scalability, performance, and maintainability.
  • Evaluate emerging LLM techniques and recommend practical adoption strategies aligned with organizational priorities.

Required Qualifications

  • 3+ years of hands-on experience working with large language models (training, fine-tuning, augmentation, or deployment).
  • Demonstrated experience integrating LLMs into production systems (e.g., semantic search, RAG pipelines, domain-specific QA).
  • Strong experience in ML system architecture and scalable deployment.
  • Proven ability to work cross-functionally with product and technical teams.
  • Experience serving as a technical SME guiding multi-team initiatives.
  • Strong programming skills in Python.
  • Experience with modern ML frameworks (e.g., PyTorch, Hugging Face) and retrieval infrastructure (e.g., embeddings, vector databases).

Preferred Qualifications

  • Experience building LLM-based systems for biomedical research or life sciences.
  • Familiarity with large scientific corpora, biomedical ontologies, structured knowledge bases, or biological datasets.
  • Experience developing generative AI systems for DNA, RNA, or protein sequence analysis.
  • Background in bioinformatics, computational biology, or related disciplines.
  • Experience improving factual grounding and reducing hallucinations in scientific or regulated environments.
Skills
PythonPyTorchHugging FaceRAGLLMsVector DatabasesEmbeddingsMachine LearningBioinformaticsRetrieval Augmented Generation