Scientist
80 – 83Baltimore, MDOnsite
Summary
Part-time Scientist supporting NIH/NIA research on age-associated protein quality control changes in aging mice using multiomics and immunolabeling techniques. Requires Master's in Biology and strong lab skills.
About the role
Responsibilities
- Implement and perform studies aimed at detecting age-associated changes in Protein Quality Control
- Perform longitudinal and cross-sectional design experiments spanning an estimated four-year period involving aging mice via a multiomics approach
- Conduct protein chemistry work including assessment of protein posttranslational modifications, protein-ligand binding, and protein-protein interactions
- Perform protein extraction/quantitation from cell and tissue lysates with strong technical background in immunolabeling (western blotting, immunofluorescence/immunohistochemistry, immunoprecipitation)
- Implement protein assays and immunolabeling assays; conduct enzymatic and protein analyses and data reduction
- Collect, analyze, and interpret data; update and maintain laboratory notebooks and databases; prepare summaries and reports
- Write scientific manuscripts; submit drafts for editing and approval; develop and deliver presentations
- Attend laboratory meetings and present results for staff discussion
- Maintain laboratory equipment and train others in their use; calibrate, maintain, and troubleshoot instruments
- Manage scientific equipment and resources including acquisition, documentation, and storage
- Evaluate new techniques, instruments, and software for potential incorporation into current SOPs
- Advance laboratory science through new procedures, discoveries, and proposing new target projects
- Work with staff on interpretation of experiments and statistical analysis for research projects
- Support planning and execution of research experiments in context of laboratory's overall research program
- Present research at national scientific meetings and symposia; prepare oral presentations and posters
Requirements
- Master's degree in Biology or related discipline
- Strong oral and written communication skills
- Proficiency with MS Office suite, PowerPoint, Outlook, and NIH POTS software
Nice-to-Haves
- Experience with HPLCs, microanalytical balances, centrifuges, spectrophotometers, vacuum apparatus, and analytical equipment
- Experience with bioinformatics data analyses and statistical analyses
- Experience writing technical reports and manuscripts
- Experience training others on scientific instrumentation and software
Skills
Protein chemistryImmunolabelingWestern blottingImmunofluorescenceImmunohistochemistryImmunoprecipitationProtein extractionProtein assaysData analysisBioinformatics