# Member of Technical Staff - System Engineering
**Company:** [Phylo](https://hotfix.jobs/companies/phylo)
**Location:** South San Francisco, CA
**Salary:** $200K-$300K
**Skills:** Kubernetes, Terraform, Python, Go, Rust, AWS, GCP, Azure, Pulumi, Distributed Systems
**Posted:** 2026-04-05
> Builds and operates core distributed systems, infrastructure, and service architecture for Phylo's agentic AI platform, ensuring reliable scaled execution across cloud and enterprise environments. Requires 3+ years in backend/infrastructure engineering with Kubernetes and cloud expertise.
## Job Description
## Responsibilities
- Design and build production systems that orchestrate agent execution and power AI-driven scientific workloads.
- Build and operate scalable, reliable infrastructure across cloud, hybrid, and on-prem enterprise environments.
- Develop systems for sandboxed execution, secure task isolation, and controlled compute environments.
- Design and implement security, access control, and compliance foundations suitable for enterprise deployments.
- Partner closely with ML and science teams to translate computational workflows into robust, production-grade distributed systems.

## Requirements
- 3+ years of industry experience in backend, infrastructure, or distributed systems engineering.
- Strong proficiency in at least one programming language (**Python**, **Go**, **Rust**, or similar).
- Experience designing and operating distributed systems in production.
- Deep hands-on experience with containerization and **Kubernetes**.
- Experience with infrastructure-as-code tooling (**Terraform**, **Pulumi**, or equivalent).
- Experience operating systems on at least one major cloud provider (**AWS**, **GCP**, or **Azure**).
- Comfort owning systems end-to-end in fast-moving, high-autonomy environments.

## Nice to Haves
- Experience building enterprise SaaS platform that supports single-tenant, customer hosted deployment patterns.
- Experience in building R&D infrastructure at Pharma/Biotech.
- Experience with job orchestration, task scheduling, or workflow engines.
- Experience with sandboxed or isolated execution frameworks (**gVisor**, **Kata Containers**, **Firecracker**).
- Familiarity with distributed storage, observability systems, or high-performance compute environments.

## Compensation & Benefits
- Competitive salary and equity share.
- Full medical, dental, and vision coverage, including free therapy sessions and eyewear stipend.
- 401(k).
- Unlimited PTO (US only).
- Lunch and snacks when in office.
- Regular team offsites and company events.
**Apply:** https://hotfix.jobs/jobs/member-of-technical-staff-system-engineering-at-phylo-353c9f74-9f07-4111-a6cf-0c10bb84424f
**Canonical:** https://hotfix.jobs/jobs/member-of-technical-staff-system-engineering-at-phylo-353c9f74-9f07-4111-a6cf-0c10bb84424f