# Threat Intel Manager, CBRN-E & Advanced Weapons

**Company:** [Anthropic](https://hotfix.jobs/companies/anthropic)
**Location:** San Francisco, CA, New York, NY, Washington, DC
**Role:** Security Engineering
**Salary:** $375k – $455k/yr
**Experience:** 7+ years
**Skills:** Threat Intelligence, Biosecurity, Cbrn-E, Weapons Non-Proliferation, Dual-Use Research Of Concern, Threat Actor Profiling, LLMs, Stakeholder Management, Government Engagement, Counterproliferation, Ai Safety, Machine Learning Security
**Posted:** 2026-07-08

> Lead and build Anthropic's CBRN-E & Advanced Weapons threat intelligence team. Investigate and disrupt AI misuse for chemical, biological, radiological, nuclear, explosives, and novel weapons development; manage investigators, engage government partners, and inform AI safety strategies. Requires deep biosecurity/weapons expertise, team leadership, and LLM knowledge.

## Job Description

## Key Responsibilities
- Own strategy, priorities, and outcomes for the CBRN-E & Advanced Weapons mission area; mature it from an emerging function into a rigorous investigative program.
- Hire, manage, and develop a team of investigators with deep domain expertise across biological, chemical, and weapons-development threat areas.
- Personally lead investigations into attempts to use our systems to develop, enhance, or disseminate CBRN-E weapons, or advanced weapons capabilities.
- Evolve detection from broad harm screens toward CBRN-specific signals and methodologies tailored to dual-use research concerns, in partnership with our collections engineers.
- Set the analytic quality bar: cross-platform threat analysis grounded in real threat actor behavior, open-source research, and publicly reported weapons programs.
- Own escalation and enforcement decisions with policy and enforcement teams for the highest-severity misuse category we handle.
- Lead external engagement with government agencies, biosecurity and chemical-security research communities, and scientific organizations.
- Inform safety-by-design and capability-evaluation strategies by forecasting how threat actors will leverage frontier AI for CBRN-E purposes.
- Serve as a liaison to government partners, educating stakeholders on AI-enabled threats through regular reporting and briefings.

## Minimum Qualifications
- Intelligence analyst, policy expert, or researcher with deep domain expertise in biosecurity, chemical defense, weapons non-proliferation, dual-use research of concern (DURC), or related CBRN-E threat domains.
- Led investigative or analytic teams; senior domain expert with demonstrated mentorship and program-building experience.
- Experience with threat actor profiling, threat intelligence analysis frameworks, and collection frameworks.
- Hands-on experience with large language models and how AI could be misused for CBRN-E threats.
- Excellent stakeholder management skills across researchers, policy experts, legal teams, government, and external partners.
- Can present analytical work to technical and non-technical audiences, including government stakeholders and senior leadership.

## Preferred Qualifications
- Advanced degree (MS or PhD) in biological sciences, chemistry, biodefense, biosecurity, or a related field.
- Real-world experience countering weapons of mass destruction or other high-risk asymmetric threats in the intelligence community or defense organizations.
- Experience working with government agencies, defense/national security organizations, or in regulated environments handling sensitive CBRN-E programs, counterproliferation and threat analysis.
- Background in AI safety, machine learning security, or technology abuse investigation.
- Experience building and scaling threat detection systems or abuse monitoring programs.
- Active Top Secret security clearance.

## Compensation & Logistics
- Annual compensation range: $375,000–$455,000 USD (total compensation).
- Minimum education: Bachelor’s degree or equivalent.
- Location-based hybrid policy: Expect staff in one of our offices at least 25% of the time.
- May require responding to escalations during weekends and holidays.
- May involve exposure to explicit content of a sexual, violent, or psychologically disturbing nature.

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